- Windows 10 RS4, RS5, and 19h1
- Windows Server 2016 (LTSC)
- Windows 7 *
- Windows 8.1 *
- Windows Server 2008 R2 *
- Windows Server 2012 R2 *
Note: Supported platforms with an asterisk are no longer supported under Microsoft Mainstream support. Therefore, proper operations of Desktop TDE on these systems cannot be guaranteed. Desktop TDE is not supported on Windows ARM systems (32-bit & 64-bit)